Pure Form Global

1. CBD appears to have calming effects. CBD may have effects similar to antidepressants. In tests against placebo, CBD has reduced anxiety in public speaking. 2. CBD is approved for drug use against epilepsy. Epidiolex contains CBD, and is approved by the FDA, and is used for use in Lennox-Gastaut Syndrome and Dravet Syndrome, two forms of epilepsy. 3. CBD may be useful in treating PTSD. CBD may help in opioid addiction. The body’s endocannabinoid system communicates with the body’s endo-opioid system. CBD has been used in heroin craving. 4. CBD may have the power to help alleviate symptoms of ALS, Lou Gehrig’s Disease. CBD has neuroprotective power and may be of use in neurodegenerative disorders. CBD may help relieve some forms of pain. CBD in pain control can be used topically. Inflammatory pain is not the same as neurogenic pain. CBD has many applications in dermatology and skin care. CBD may help in slowing the progression of Parkinson’s disease. CBD has been shown to be of promis...

Fibromyalgia is a poorly understood syndrome, characterized by chronic widespread pain, fatigue, and sleep disturbance. It appears to involve an alteration of central pain pathways, in which mast cells, which mediate activation of microglia through cytokines like interleukin 1 beta (IL-1B), interleukin 6 (IL-6), and tumor necrosis factor (TNF) alpha, play a central role. It may as well overlap with other conditions. Existing treatments, none of them completely satisfactory, include memantine, naltrexone, tapentadol, duloxetine, and palmitoylethanolamide.  Cannabinoids may be of promise. This is because they generally show anti-inflammatory and immunomodulatory activity, and often possess a demonstrated analgesic capability, acting on cannabinoid receptors and inhibiting presynaptic gamma-aminobutyric acid (GABA) and glutamatergic transmission. For reasons not completely known, activation of receptors CB1 and CB2 in general seems to have anti-pain-perception effects overall. The exa...